Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzymes (ACE, kinase II). Angiotensin II is the main pressor agent of the renin-angiotensin system, whose actions include vasoconstriction, stimulation of aldosterone synthesis and release, cardiac stimulation and sodium reabsorption.
Candesartan inhibits the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Therefore, its effect is independent of angiotensin II synthesis pathways.
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Manufactured By |
AMARANT PHARMACEUTICALS (PVT) LTD |
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Product Form |
tablet |
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Flavor |
Bitter |
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Generic Category |
PSYCHOSIS |
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Active Ingredient |
Risperidone |
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Age |
As per doctor |
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Recommended Dosage |
As per Physicians |
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Prescription |
Yes |
- The mechanism of action of risperidone in the treatment of schizophrenia is unclear.
- The therapeutic effect of the drug in the treatment of schizophrenia may be mediated by antagonism of dopamine type 2 (D2) and serotonin type 2 (5HT2) receptors.
- The clinical effect of risperidone results from the combined concentrations of risperidone and its main metabolite, 9-hydroxyrisperidone (paliperidone).
- Antagonism at receptors other than D2 and 5HT2 receptors may explain some of the other effects of risperidone.
- Increased mortality in elderly patients with dementia-related psychosis.
- Cerebrovascular adverse events, including stroke, in elderly patients with dementia-related psychosis
- Neuroleptic malignant syndrome.
- Tardive dyskinesia
Does nrotis tablet cause hypersensitivity?
Yes, in some cases it caused hypersensitivity.
Frequent use of neoris can cause constipation?
Yes, some cases are reported. But it is not clinically proven.
Is it okay to have neoris in my pregnancy?
You should have to consult your doctor if you are going to start neoris or have it.